Urban Environment Design Studio is organized in collaboration with Columbia University (New York City). The studio aims at promoting an active collaboration among University of Genoa and Columbia University students in a joint project to their mutual benefit. The project site is the area of Quarto (Genoa), including the former psychiatric hospital, a partially dismissed and valuable area, the lower Sturla river basin, its mouth, and the coastline. The studio is based on an active involvement of the Municipality of Genoa as client. The students are asked to identify development strategies at the urban scale, focusing on some specific areas (at the building scale), considering economic and environmental sustainability as well as landscape enhancement.